Neuroinflammation in Huntington's Disease
In Huntington’s disease, the immune system of the brain is constantly trying to attack and remove the mutant huntingtin protein. But over time, this immune response called neuroinflammation can also become toxic to healthy brain cells!
Understanding and measuring neuroinflammation will help us to work out how much this immune response contributes to the progression of HD, and how we may be able to stop it.
How am I investigating inflammation?
This project uses combined Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) brain scanning, as well as blood tests and genetic analysis.
What will we learn from this research?
Your participation will contribute to our growing understanding of how the brain changes in HD, including new insights into how we may be able to track or treat this disorder in the future.
This study is not currently recruiting participants.
Ethics Approval: Monash University Research Ethics Committee (MUHREC) 2017-7810.